GLI1 Monoclonal Antibody
- SKU:
- CAB23236
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | GLI1 Monoclonal Antibody |
| Product Code: | CAB23236 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59108 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A-549 |
| Cellular Location: | Cytoplasm, Nucleus |
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human GLI1 (NP_005260.1). |
| Sequence: | MFNSM TPPPI SSYGE PCCLR PLPSQ GAPSV GTEGL SGPPF CHQAN LMSGP HSYGP ARETN SCTEG PLFSS PRSAV KLTKK RALSI SPLSD ASLDL QTVIR TSPSS LVAFI NSRCT SPGGS YGHLS IGTMS PSLGF PAQMN HQKGP SPSFG VQPCG PHDSA RGGMI PHPQS RGPFP TCQLK SELDM LVGKC REEPL EGDMS SPNST GIQDP LLGML DGRED LEREE KREPE SVY |
| Synonyms: | GLI, PPD1, PAPA8 |
| Calculated MW: | 118kDa |
| Observed MW: | 160kDa |
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