gL Antibody (PACO35082)
- SKU:
- PACO35082
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | gL Antibody (PACO35082) |
| Antibody SKU: | PACO35082 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human cytomegalovirus |
| Immunogen: | Recombinant Human cytomegalovirus Envelope glycoprotein L protein (31-278AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| Synonyms: | Envelope glycoprotein L (gL), gL |
| UniProt Protein Function: | The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | F5HCH8 |
| NCBI GenInfo Identifier: | 52139280 |
| NCBI Gene ID: | 3077416 |
| NCBI Accession: | YP_081555.1 |
| UniProt Secondary Accession: | F5HCH8 |
| UniProt Related Accession: | F5HCH8,Q71DN9 |
| Molecular Weight: | 29.5 kDa |
| NCBI Full Name: | envelope glycoprotein L |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | UL115 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | contains signal peptide; complexed with envelope glycoprotein H; involved in cell entry; involved in cell-to-cell spread |
| UniProt Protein Name: | Envelope glycoprotein L |
| UniProt Synonym Protein Names: | |
| Protein Family: | Envelope glycoprotein |
| UniProt Gene Name: | gL |
| UniProt Entry Name: | GL_HCMVM |
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