Name: GK/GK3P Antibody (PACO00856)
SKU: PACO00856
Availability: OutOfStock

Antibody Name:	GK/GK3P Antibody
Antibody SKU:	PACO00856
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:	Human
Immunogen:	synthesized peptide derived from the N-terminal region of human GK1/3.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

GK; Glycerol kinase; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase; GK3P; GKP3; GKTB; Putative glycerol kinase 3; GK 3; Glycerokinase 3; ATP:glycerol 3-phosphotransferase 3; Glycerol kinase; testis specific 1

UniProt Protein Function:	GLPK: Key enzyme in the regulation of glycerol uptake and metabolism. Defects in GK are the cause of GK deficiency (GKD). This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only. Belongs to the FGGY kinase family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:EC 2.7.1.30; Lipid Metabolism - glycerolipid; Mitochondrial; Kinase, other Chromosomal Location of Human Ortholog: Xp21.3 Cellular Component: mitochondrial outer membrane; cytosol; nucleus Molecular Function:glycerol kinase activity; protein binding; ATP binding Biological Process: triacylglycerol metabolic process; glycerol metabolic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; glucose homeostasis; phosphorylation; glycerol-3-phosphate biosynthetic process; glycerol catabolic process Disease: Glycerol Kinase Deficiency
NCBI Summary:	The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
UniProt Code:	P32189
NCBI GenInfo Identifier:	205830913
NCBI Gene ID:	2710
NCBI Accession:	P32189.3
UniProt Secondary Accession:	P32189,Q6IQ27, Q8IVR5, Q9UMP0, Q9UMP1, A6NJP5, B2R833
UniProt Related Accession:	P32189
Molecular Weight:	58,141 Da
NCBI Full Name:	Glycerol kinase
NCBI Synonym Full Names:	glycerol kinase
NCBI Official Symbol:	GK
NCBI Official Synonym Symbols:	GK1; GKD
NCBI Protein Information:	glycerol kinase; ATP:glycerol 3-phosphotransferase; glycerokinase
UniProt Protein Name:	Glycerol kinase
UniProt Synonym Protein Names:	ATP:glycerol 3-phosphotransferase
Protein Family:	Glycerol kinase
UniProt Gene Name:	GK
UniProt Entry Name:	GLPK_HUMAN