Description
| Antibody Name: | GJB7 Antibody (PACO37014) |
| Antibody SKU: | PACO37014 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Gap junction beta-7 protein (41-75AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of A431 cells using PACO37014 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Synonyms: | Gap junction beta-7 protein (Connexin-25) (Cx25), GJB7, CX25 |
| UniProt Protein Function: | GJB7: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 6q15Cellular Component: connexon complex; integral to membraneBiological Process: cell communication |
| UniProt Protein Details: | |
| NCBI Summary: | Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6PEY0 |
| NCBI GenInfo Identifier: | 74749171 |
| NCBI Gene ID: | 375519 |
| NCBI Accession: | Q6PEY0.1 |
| UniProt Secondary Accession: | Q6PEY0,Q96KP0, B3KXL0 |
| UniProt Related Accession: | Q6PEY0 |
| Molecular Weight: | 25,860 Da |
| NCBI Full Name: | Gap junction beta-7 protein |
| NCBI Synonym Full Names: | gap junction protein beta 7 |
| NCBI Official Symbol: | GJB7 |
| NCBI Official Synonym Symbols: | CX25; bA136M9.1; connexin25 |
| NCBI Protein Information: | gap junction beta-7 protein |
| UniProt Protein Name: | Gap junction beta-7 protein |
| UniProt Synonym Protein Names: | Connexin-25; Cx25 |
| Protein Family: | Gap junction beta-7 protein |
| UniProt Gene Name: | GJB7 |
| UniProt Entry Name: | CXB7_HUMAN |
| Antibodies |
| GJB7 Antibody (PACO00625) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
