Description
Antibody Name: | GJB7 Antibody (PACO22344) |
Antibody SKU: | PACO22344 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human GJB7. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from HT-29 cells, using GJB7 antibody. |
Background: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell By similarity. |
Synonyms: | connexin25; CX25; CXB7; gap junction protein; beta 7 |
UniProt Protein Function: | GJB7: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 6q15Cellular Component: connexon complex; integral to membraneBiological Process: cell communication |
UniProt Protein Details: | |
NCBI Summary: | Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6PEY0 |
NCBI GenInfo Identifier: | 74749171 |
NCBI Gene ID: | 375519 |
NCBI Accession: | Q6PEY0.1 |
UniProt Secondary Accession: | Q6PEY0,Q96KP0, B3KXL0 |
UniProt Related Accession: | Q6PEY0 |
Molecular Weight: | 25,860 Da |
NCBI Full Name: | Gap junction beta-7 protein |
NCBI Synonym Full Names: | gap junction protein beta 7 |
NCBI Official Symbol: | GJB7 |
NCBI Official Synonym Symbols: | CX25; bA136M9.1; connexin25 |
NCBI Protein Information: | gap junction beta-7 protein |
UniProt Protein Name: | Gap junction beta-7 protein |
UniProt Synonym Protein Names: | Connexin-25; Cx25 |
Protein Family: | Gap junction beta-7 protein |
UniProt Gene Name: | GJB7 |
UniProt Entry Name: | CXB7_HUMAN |
Antibodies |
GJB7 Antibody (PACO00625) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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