Description
| Antibody Name: | GJB5 Antibody (PACO26993) |
| Antibody SKU: | PACO26993 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Gap junction beta-5 protein (211-273AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO26993 at dilution of 1:100. |
![]() | Immunofluorescent analysis of A549 cells using PACO26993 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Synonyms: | Gap junction beta-5 protein (Connexin-31.1) (Cx31.1), GJB5 |
| UniProt Protein Function: | GJB5: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Beta-type (group I) subfamily.Protein type: Cell adhesion; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1p35.1Biological Process: epidermis development |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the beta-type (group I) connexin family. The encoded protein is a gap junction protein involved in intercellular communication related to epidermal differentiation and environmental sensing. This gene has been linked to non-small cell lung cancer. [provided by RefSeq, Nov 2012] |
| UniProt Code: | O95377 |
| NCBI GenInfo Identifier: | 8928551 |
| NCBI Gene ID: | 2709 |
| NCBI Accession: | O95377.2 |
| UniProt Secondary Accession: | O95377,Q9UPA3 |
| UniProt Related Accession: | O95377 |
| Molecular Weight: | 31,088 Da |
| NCBI Full Name: | Gap junction beta-5 protein |
| NCBI Synonym Full Names: | gap junction protein beta 5 |
| NCBI Official Symbol: | GJB5 |
| NCBI Official Synonym Symbols: | CX31.1 |
| NCBI Protein Information: | gap junction beta-5 protein |
| UniProt Protein Name: | Gap junction beta-5 protein |
| UniProt Synonym Protein Names: | Connexin-31.1; Cx31.1 |
| Protein Family: | Gap junction beta-5 protein |
| UniProt Gene Name: | GJB5 |
| UniProt Entry Name: | CXB5_HUMAN |

