GJA9 Antibody (PACO17740)
- SKU:
- PACO17740
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GJA9 Antibody (PACO17740) |
| Antibody SKU: | PACO17740 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human GJA9 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal muscle tissue, Primary antibody: PACO17740(GJA9 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
| Background: | Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Synonyms: | gap junction protein, α 9, 59kDa |
| UniProt Protein Function: | GJA9: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Alpha-type (group II) subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p34 Cellular Component: connexon complex; integral to membrane Biological Process: cell communication |
| NCBI Summary: | Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | P57773 |
| NCBI GenInfo Identifier: | 50403749 |
| NCBI Gene ID: | 81025 |
| NCBI Accession: | P57773.2 |
| UniProt Secondary Accession: | P57773,Q5TA63, Q96KG0, B2R722, B3KVQ2, |
| UniProt Related Accession: | P57773 |
| Molecular Weight: | 515 |
| NCBI Full Name: | Gap junction alpha-9 protein |
| NCBI Synonym Full Names: | gap junction protein, alpha 9, 59kDa |
| NCBI Official Symbol: | GJA9 |
| NCBI Official Synonym Symbols: | CX58; CX59; GJA10 |
| NCBI Protein Information: | gap junction alpha-9 protein; connexin 59; connexin-58; gap junction alpha 10 |
| UniProt Protein Name: | Gap junction alpha-9 protein |
| UniProt Synonym Protein Names: | Connexin-58; Cx58; Connexin-59; Cx59; Gap junction alpha-10 protein |
| Protein Family: | Gap junction alpha-9 protein |
| UniProt Gene Name: | GJA9 |
| UniProt Entry Name: | CXA9_HUMAN |
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