GIRK2(KCNJ6) Monoclonal Antibody
- SKU:
- CAB24391
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | GIRK2(KCNJ6) Monoclonal Antibody |
| Product Code: | CAB24391 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63224 |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T |
| Cellular Location: | Membrane, Multi-pass membrane protein |
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GIRK2(NP_002231.1). |
| Sequence: | MAKLT ESMTN VLEGD SMDQD VESPV AIHQP KLPKQ ARDDL PRHIS RDRTK RKIQR YVRKD GKCNV HHGNV RETYR YLTDI FTTLV DLKWR FNLLI FVMVY |
| Synonyms: | BIR1, GIRK2, KATP2, KCNJ7, KPLBS, GIRK-2, KATP-2, KIR3.2, hiGIRK2 |
| Calculated MW: | 48kDa |
| Observed MW: | 48kDa |
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