Name: GHITM Antibody (PACO41062)
SKU: PACO41062
Availability: OutOfStock

Antibody Name:	GHITM Antibody (PACO41062)
Antibody SKU:	PACO41062
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:500
Species Reactivity:	Human, Rat
Immunogen:	Recombinant Human Growth hormone-inducible transmembrane protein (293-345AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot. Positive WB detected in: Rat brain tissue. All lanes: GHITM antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa.
	IHC image of PACO41062 diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
	IHC image of PACO41062 diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Background:	Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Synonyms:	Growth hormone-inducible transmembrane protein (Dermal papilla-derived protein 2) (Mitochondrial morphology and cristae structure 1) (MICS1) (Transmembrane BAX inhibitor motif-containing protein 5), GHITM, DERP2 MICS1 TMBIM5

UniProt Protein Function:	GHITM: Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. Belongs to the BI1 family.
UniProt Protein Details:	Protein type:Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 10q23.1 Cellular Component: integral to membrane; mitochondrial inner membrane Molecular Function:protein binding Biological Process: apoptosis
UniProt Code:	Q9H3K2
NCBI GenInfo Identifier:	15213977
NCBI Gene ID:	27069
NCBI Accession:	Q9H3K2.2
UniProt Secondary Accession:	Q9H3K2,O95894, Q5VT95, Q9H0P2, A8K9Z9, D3DWE0,
UniProt Related Accession:	Q9H3K2
Molecular Weight:	37,205 Da
NCBI Full Name:	Growth hormone-inducible transmembrane protein
NCBI Synonym Full Names:	growth hormone inducible transmembrane protein
NCBI Official Symbol:	GHITM
NCBI Official Synonym Symbols:	DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282
NCBI Protein Information:	growth hormone-inducible transmembrane protein
UniProt Protein Name:	Growth hormone-inducible transmembrane protein
UniProt Synonym Protein Names:	Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5
Protein Family:	Growth hormone-inducible transmembrane protein
UniProt Gene Name:	GHITM
UniProt Entry Name:	GHITM_HUMAN

Antibodies	ELISA Kits
GHITM Antibody (PACO03879)	Human MICS1 / GHITM ELISA Kit
GHITM Antibody (PACO09463)	Human GHITM (Growth Hormone Inducible Transmembrane Protein) CLIA Kit (HUES01060)

Secondary Antibody