GH2 Antibody (PACO26969)
- SKU:
- PACO26969
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GH2 Antibody (PACO26969) |
| Antibody SKU: | PACO26969 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Growth hormone variant protein (27-217AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: GH2 antibody at 16µg/ml + Mouse skeletal muscle tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 25, 29, 24, 28 kDa Observed band size: 25 kDa . |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO26969 at dilution of 1:100. |
| Background: | Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid, uptake and protein synthesis in muscle and other tissues. |
| Synonyms: | Growth hormone variant (GH-V) (Growth hormone 2) (Placenta-specific growth hormone), GH2 |
| UniProt Protein Function: | GH2: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Belongs to the somatotropin/prolactin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: extracellular region |
| NCBI Summary: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P01242 |
| NCBI GenInfo Identifier: | 20141664 |
| NCBI Gene ID: | 2689 |
| NCBI Accession: | P01242.3 |
| UniProt Secondary Accession: | P01242,O14643, O14644, P09587, B1A4H5, B1A4H7, |
| UniProt Related Accession: | P01242 |
| Molecular Weight: | 27,101 Da |
| NCBI Full Name: | Growth hormone variant |
| NCBI Synonym Full Names: | growth hormone 2 |
| NCBI Official Symbol: | GH2 |
| NCBI Official Synonym Symbols: | GHL; GHV; GH-V; GHB2; hGH-V |
| NCBI Protein Information: | growth hormone variant |
| UniProt Protein Name: | Growth hormone variant |
| UniProt Synonym Protein Names: | Growth hormone 2; Placenta-specific growth hormone |
| Protein Family: | Growth hormone |
| UniProt Gene Name: | GH2 |
| UniProt Entry Name: | SOM2_HUMAN |
| Antibodies | ELISA Kits |
| GH2 Antibody (PACO09462) | Human GH2 / Growth Hormone 2 ELISA Kit |
| Human GH2 (Growth Hormone 2) CLIA Kit (HUES01058) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human GH2 / Growth Hormone 2 ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
