Description
system_update_alt Datasheet
Product Name: | GH1 Antibody |
Product Sku: | CPAB0048 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | GH Antibody is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant Growth hormone. |
Clone: | PG3H5AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | GH antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. |
Synonyms: | GH1, GH, GHN, GH-N, hGH-N, Pituitary growth hormone, Growth hormone 1, Somatotropin. |
Storage Buffer: | For periods up to 1 month store at 4 C, for longer periods of time, store at -20 C. Prevent freeze thaw cycles. |