Description
| Antibody Name: | GFRAL Antibody, HRP conjugated (PACO36907) |
| Antibody SKU: | PACO36907 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human GDNF family receptor alpha-like protein (19-351AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | HRP |
| Background: | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. |
| Synonyms: | GDNF family receptor alpha-like, GFRAL, C6orf144 |
| UniProt Protein Function: | GFRAL: Belongs to the GDNFR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p12.1Cellular Component: integral to membrane; intracellular; plasma membraneBiological Process: negative regulation of neuron apoptosis; stress-activated protein kinase signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UXV0 |
| NCBI GenInfo Identifier: | 148231468 |
| NCBI Gene ID: | 389400 |
| NCBI Accession: | NP_997293.2 |
| UniProt Secondary Accession: | Q6UXV0,Q5VTF6 |
| UniProt Related Accession: | Q6UXV0 |
| Molecular Weight: | |
| NCBI Full Name: | GDNF family receptor alpha-like |
| NCBI Synonym Full Names: | GDNF family receptor alpha like |
| NCBI Official Symbol: | GFRAL |
| NCBI Official Synonym Symbols: | GRAL; UNQ9356; C6orf144; bA360D14.1 |
| NCBI Protein Information: | GDNF family receptor alpha-like |
| UniProt Protein Name: | GDNF family receptor alpha-like |
| UniProt Synonym Protein Names: | |
| Protein Family: | GDNF family receptor |
| UniProt Gene Name: | GFRAL |
| UniProt Entry Name: | GFRAL_HUMAN |