Description
Antibody Name: | GFRAL Antibody, HRP conjugated (PACO36907) |
Antibody SKU: | PACO36907 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human GDNF family receptor alpha-like protein (19-351AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | HRP |
Background: | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. |
Synonyms: | GDNF family receptor alpha-like, GFRAL, C6orf144 |
UniProt Protein Function: | GFRAL: Belongs to the GDNFR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p12.1Cellular Component: integral to membrane; intracellular; plasma membraneBiological Process: negative regulation of neuron apoptosis; stress-activated protein kinase signaling pathway |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6UXV0 |
NCBI GenInfo Identifier: | 148231468 |
NCBI Gene ID: | 389400 |
NCBI Accession: | NP_997293.2 |
UniProt Secondary Accession: | Q6UXV0,Q5VTF6 |
UniProt Related Accession: | Q6UXV0 |
Molecular Weight: | |
NCBI Full Name: | GDNF family receptor alpha-like |
NCBI Synonym Full Names: | GDNF family receptor alpha like |
NCBI Official Symbol: | GFRAL |
NCBI Official Synonym Symbols: | GRAL; UNQ9356; C6orf144; bA360D14.1 |
NCBI Protein Information: | GDNF family receptor alpha-like |
UniProt Protein Name: | GDNF family receptor alpha-like |
UniProt Synonym Protein Names: | |
Protein Family: | GDNF family receptor |
UniProt Gene Name: | GFRAL |
UniProt Entry Name: | GFRAL_HUMAN |