Description
| Antibody Name: | GFRAL Antibody, FITC conjugated (PACO36908) | 
| Antibody SKU: | PACO36908 | 
| Size: | 50ug | 
| Host Species: | Rabbit | 
| Tested Applications: | ELISA | 
| Recommended Dilutions: | |
| Species Reactivity: | Human | 
| Immunogen: | Recombinant Human GDNF family receptor alpha-like protein (19-351AA) | 
| Form: | Liquid | 
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4  | 
| Purification Method: | >95%, Protein G purified | 
| Clonality: | Polyclonal | 
| Isotype: | IgG | 
| Conjugate: | FITC | 
| Background: | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. | 
| Synonyms: | GDNF family receptor alpha-like, GFRAL, C6orf144 | 
| UniProt Protein Function: | GFRAL: Belongs to the GDNFR family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p12.1Cellular Component: integral to membrane; intracellular; plasma membraneBiological Process: negative regulation of neuron apoptosis; stress-activated protein kinase signaling pathway | 
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UXV0 | 
| NCBI GenInfo Identifier: | 148231468 | 
| NCBI Gene ID: | 389400 | 
| NCBI Accession: | NP_997293.2 | 
| UniProt Secondary Accession: | Q6UXV0,Q5VTF6 | 
| UniProt Related Accession: | Q6UXV0 | 
| Molecular Weight: | |
| NCBI Full Name: | GDNF family receptor alpha-like | 
| NCBI Synonym Full Names: | GDNF family receptor alpha like | 
| NCBI Official Symbol: | GFRAL | 
| NCBI Official Synonym Symbols: | GRAL; UNQ9356; C6orf144; bA360D14.1 | 
| NCBI Protein Information: | GDNF family receptor alpha-like | 
| UniProt Protein Name: | GDNF family receptor alpha-like | 
| UniProt Synonym Protein Names: | |
| Protein Family: | GDNF family receptor | 
| UniProt Gene Name: | GFRAL | 
| UniProt Entry Name: | GFRAL_HUMAN |