GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL2941)

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SKU:
AGEL2941
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
PK136
Conjugation:
AFViolet 450

Description

Product Name:GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL2941)
Product Code:AGEL2941
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C,Klrb1c,CD161 antigen-like family member C,Ly-55c,CD161/NK1.1,NKR-P1.9,NKR-P1C,NKR-P1 40,CD161c
Reactivity:Mouse
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:GenieFluor Violet 450 Mouse IgG2a, κ Isotype Control [C1.18.4] (AGEL2856)
Conjugation:AFViolet 450
Form:Liquid
Fluorescent Label:AFViolet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID:17059
Swissprot:P27814,P27812,Q99JB4
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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