GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL2959)

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SKU:
AGEL2959
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
MIAP410
Conjugation:
AFViolet 450

Description

Product Name:GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL2959)
Product Code:AGEL2959
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Reactivity:Human,Mouse,Rat
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG1, κ
Isotype Control:GenieFluor Violet 450 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2854)
Conjugation:AFViolet 450
Form:Liquid
Fluorescent Label:AFViolet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID:9611642329364
Swissprot:Q08722,Q61735,P97829
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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