GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2965)
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- SKU:
- AGEL2965
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG2b, κ
- Clone:
- M1/70
- Conjugation:
- AFRed 780
Description
| Product Name: | GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2965) |
| Product Code: | AGEL2965 |
| Clone No: | M1/70 |
| Synonyms: | Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b |
| Reactivity: | Human,Mouse |
| Host Species: | Rat |
| Applications: | FCM |
| Isotype: | Rat IgG2b, κ |
| Isotype Control: | GenieFluor Red 780 Rat IgG2b, κ Isotype Control [LTF-2] (AGEL2931) |
| Conjugation: | AFRed 780 |
| Form: | Liquid |
| Fluorescent Label: | AFRed 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Gene ID: | 164093684 |
| Swissprot: | P05555,P11215 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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