Description
Product Name: | AFRed 780 Anti-Human CD64 Antibody [10.1] |
Product Code: | AGEL3319 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | 10.1 |
Synonyms: | Fc fragment of IgG high affinity Ia/b/c receptor, CD64A/B/C, CD64, Fc gamma RI, FCGR1A/B/C, IGFR 1 |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | ER780 Mouse IgM, κ Isotype Control [MM-30] |
Conjugation: | AFRed 780 |
Applications: | FCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Fluorescent Label: | GenieFluor Red 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter). |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Gene ID: | 2209 |
Swissprot: | P12314 |
Background Information: | CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC). |