GenieFluor Red 780 Anti-Human CD27 Antibody [O323]
- SKU:
- AGEL3062
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- O323
- Conjugation:
- AFRed 780
Description
| Product Name: | GenieFluor Red 780 Anti-Human CD27 Antibody [O323] |
| Product Code: | AGEL3062 |
| Clone No: | O323 |
| Synonyms: | CD27L receptor,T-cell activation antigen CD27,T14,S152,TNFRSF7 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | GenieFluor Red 780 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2920) |
| Conjugation: | AFRed 780 |
| Form: | Liquid |
| Fluorescent Label: | AFRed 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Gene ID: | 939 |
| Swissprot: | P26842 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
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