GenieFluor Red 780 Anti-Human CD14 Antibody [M5E2]

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SKU:
AGEL2998
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
M5E2
Conjugation:
AFRed 780

Description

Product Name:GenieFluor Red 780 Anti-Human CD14 Antibody [M5E2]
Product Code:AGEL2998
Clone No:M5E2
Synonyms:Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:GenieFluor Red 780 Mouse IgG2a, κ Isotype Control [C1.18.4] (AGEL2923)
Conjugation:AFRed 780
Form:Liquid
Fluorescent Label:AFRed 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID:929
Swissprot:P08571
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

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