GenieFluor Red 780 Anti-Human CD11b Antibody [ICRF44]
- SKU:
- AGEL2997
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- ICRF44
- Conjugation:
- AFRed 780
Description
Product Name: | GenieFluor Red 780 Anti-Human CD11b Antibody [ICRF44] |
Product Code: | AGEL2997 |
Clone No: | ICRF44 |
Synonyms: | Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | GenieFluor Red 780 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2920) |
Conjugation: | AFRed 780 |
Form: | Liquid |
Fluorescent Label: | AFRed 780 is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 770 nm (e.g., a 780/60 nm bandpass filter). |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Gene ID: | 3684 |
Swissprot: | P11215 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.