Description
Product Name: | GenieFluor 647 Anti-Human IL-10 Antibody [JES3-9D7] |
Product Code: | AGEL3155 |
Clone No: | JES3-9D7 |
Synonyms: | Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF |
Reactivity: | Human |
Host Species: | Rat |
Applications: | ICFCM |
Isotype: | Rat IgG1, κ |
Isotype Control: | GenieFluor 647 Rat IgG1, κ Isotype Control [HRPN] (AGEL2627) |
Conjugation: | AF647 |
Form: | Liquid |
Fluorescent Label: | AF647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Gene ID: | 3586 |
Swissprot: | P22301 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.