GenieFluor 488 Anti-Human CD4 Antibody [SK3]
- SKU:
- AGEL3447
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, k
- Clone:
- SK3
- Conjugation:
- AF488
Description
Product Name: | AF488 Anti-Human CD4 Antibody [SK3] |
Product Code: | AGEL3447 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | SK3 |
Synonyms: | T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3 |
Reactivity: | Human |
Host Species: | Mouse |
Applications: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | AF488 Mouse IgG1, κ Isotype Control [MOPC-21] |
Conjugation: | AF488 |
Applications: | FCM |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Fluorescent Label: | GenieFluor 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
Shipping: | Biological ice pack at 4°C |
Form: | Liquid |
Gene ID: | 920 |
Swissprot: | P01730 |
Background Information: | CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |