GenieFluor 488 Anti-Human CD34 Antibody [4H11]
- SKU:
- AGEL3441
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, k
- Clone:
- 4H11
- Conjugation:
- AF488
Description
| Product Name: | AF488 Anti-Human CD34 Antibody [4H11] |
| Product Code: | AGEL3441 |
| Size: | 20 Tests, 100 Tests, 200 Tests |
| Clone No: | 4H11 |
| Synonyms: | Gp105-120, My10 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | AF488 Mouse IgG1, κ Isotype Control [MOPC-21] |
| Conjugation: | AF488 |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Fluorescent Label: | GenieFluor 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 947 |
| Swissprot: | P28906 |
| Background Information: | CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands. |
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