GenieFluor 488 Anti-Human CD161 Antibody [HP-3G10]
- SKU:
- AGEL2284
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- HP-3G10
- Conjugation:
- AF488
Description
| Product Name: | GenieFluor 488 Anti-Human CD161 Antibody [HP-3G10] |
| Product Code: | AGEL2284 |
| Clone No: | HP-3G10 |
| Synonyms: | CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | GenieFluor 488 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2557) |
| Conjugation: | AF488 |
| Form: | Liquid |
| Fluorescent Label: | AF488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Swissprot: | Q12918 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
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