GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]
![GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/87905/91808/geniefluor-488-anti-human-cd107alamp-1-antibody-h4a3__33298__86323.1706550110.jpg?c=1 "GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]")
- SKU:
- AGEL3150
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- Mouse IgG1, κ
- Clone:
- H4A3
- Conjugation:
- AF488
![GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/87905/91808/geniefluor-488-anti-human-cd107alamp-1-antibody-h4a3__33298__86323.1706550110.jpg?c=1&imbypass=on "GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3]")
Description
| Product Name: | GenieFluor 488 Anti-Human CD107a/LAMP-1 Antibody [H4A3] |
| Product Code: | AGEL3150 |
| Clone No: | H4A3 |
| Synonyms: | Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1 |
| Reactivity: | Human |
| Host Species: | Mouse |
| Applications: | FCM |
| Isotype: | Mouse IgG1, κ |
| Isotype Control: | GenieFluor 488 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2557) |
| Conjugation: | AF488 |
| Form: | Liquid |
| Fluorescent Label: | AF488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Gene ID: | 3916 |
| Swissprot: | P11279 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
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Human CD107a/LAMP-1 Monoclonal Antibody (PE Conjugated) [H4A3](AGEL1775)
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