GDPD2 Antibody (PACO40614)
- SKU:
- PACO40614
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GDPD2 Antibody (PACO40614) |
| Antibody SKU: | PACO40614 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Glycerophosphoinositol inositolphosphodiesterase GDPD2 protein (210-490AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: GDPD2 antibody at 1.5µg/ml + A431 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62, 53, 67 kDa. Observed band size: 62 kDa. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO40614 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40614 at dilution of 1:100. |
| Background: | Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity). |
| Synonyms: | Glycerophosphoinositol inositolphosphodiesterase GDPD2 (EC 3.1.4.43) (Glycerophosphodiester phosphodiesterase 3) (Glycerophosphodiester phosphodiesterase domain-containing protein 2) (Osteoblast differentiation promoting factor), GDPD2, GDE3 OBDPF |
| UniProt Protein Function: | GDPD2: Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton. Belongs to the glycerophosphoryl diester phosphodiesterase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integral; Phosphodiesterase; EC 3.1.4.43Chromosomal Location of Human Ortholog: Xq13.1 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q9HCC8 |
| NCBI GenInfo Identifier: | 74752794 |
| NCBI Gene ID: | 54857 |
| NCBI Accession: | Q9HCC8.1 |
| UniProt Secondary Accession: | Q9HCC8,Q9NXJ6, B4DRH4, B4DVC9 |
| UniProt Related Accession: | Q9HCC8 |
| Molecular Weight: | 66,991 Da |
| NCBI Full Name: | Glycerophosphoinositol inositolphosphodiesterase GDPD2 |
| NCBI Synonym Full Names: | glycerophosphodiester phosphodiesterase domain containing 2 |
| NCBI Official Symbol: | GDPD2 |
| NCBI Official Synonym Symbols: | GDE3; OBDPF |
| NCBI Protein Information: | glycerophosphoinositol inositolphosphodiesterase GDPD2 |
| UniProt Protein Name: | Glycerophosphoinositol inositolphosphodiesterase GDPD2 |
| UniProt Synonym Protein Names: | Glycerophosphodiester phosphodiesterase 3; Glycerophosphodiester phosphodiesterase domain-containing protein 2; Osteoblast differentiation promoting factor |
| Protein Family: | Glycerophosphodiester phosphodiesterase |
| UniProt Gene Name: | GDPD2 |
| UniProt Entry Name: | GDPD2_HUMAN |
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