GBP6 Antibody (PACO36914)
- SKU:
- PACO36914
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GBP6 Antibody (PACO36914) |
| Antibody SKU: | PACO36914 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Guanylate-binding protein 6 protein (401-600AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO36914 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO36914 at dilution of 1:100. |
| Background: | Binds GTP, GDP and GMP. |
| Synonyms: | Guanylate-binding protein 6 (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6), GBP6 |
| UniProt Protein Function: | GBP6: Binds GTP, GDP and GMP. Belongs to the GBP family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: HydrolaseChromosomal Location of Human Ortholog: 1p22.2Molecular Function: GTPase activity; GTP bindingBiological Process: metabolic process; defense response to bacterium; immune response |
| UniProt Protein Details: | |
| NCBI Summary: | Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et al., 2006 [PubMed 16689661]).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q6ZN66 |
| NCBI GenInfo Identifier: | 74749570 |
| NCBI Gene ID: | 163351 |
| NCBI Accession: | Q6ZN66.1 |
| UniProt Secondary Accession: | Q6ZN66,Q6ZN86, Q7Z3F0, A2RRM3 |
| UniProt Related Accession: | Q6ZN66 |
| Molecular Weight: | |
| NCBI Full Name: | Guanylate-binding protein 6 |
| NCBI Synonym Full Names: | guanylate binding protein family, member 6 |
| NCBI Official Symbol: | GBP6 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | guanylate-binding protein 6; GBP-6; GTP-binding protein 6; guanine nucleotide-binding protein 6 |
| UniProt Protein Name: | Guanylate-binding protein 6 |
| UniProt Synonym Protein Names: | GTP-binding protein 6; GBP-6; Guanine nucleotide-binding protein 6 |
| Protein Family: | Guanylate-binding protein |
| UniProt Gene Name: | GBP6 |
| UniProt Entry Name: | GBP6_HUMAN |
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