Description
| Antibody Name: | GBP4 Antibody |
| Antibody SKU: | PACO02432 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human GBP4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | GBP4; Guanylate-binding protein 4; GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4 |
| UniProt Protein Function: | GBP4: Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation. Belongs to the GBP family. |
| UniProt Protein Details: | Protein type:Cell adhesion; Hydrolase; Vesicle Chromosomal Location of Human Ortholog: 1p22.2 Cellular Component: Golgi membrane; nucleus; perinuclear region of cytoplasm Molecular Function:GTP binding; GTPase activity Biological Process: metabolic process |
| NCBI Summary: | Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008] |
| UniProt Code: | Q96PP9 |
| NCBI GenInfo Identifier: | 116242487 |
| NCBI Gene ID: | 115361 |
| NCBI Accession: | Q96PP9.2 |
| UniProt Secondary Accession: | Q96PP9,Q05D63, Q6NSL0, Q86T99, B2R630, |
| UniProt Related Accession: | Q96PP9 |
| Molecular Weight: | 73,165 Da |
| NCBI Full Name: | Guanylate-binding protein 4 |
| NCBI Synonym Full Names: | guanylate binding protein 4 |
| NCBI Official Symbol: | GBP4 |
| NCBI Official Synonym Symbols: | Mpa2 |
| NCBI Protein Information: | guanylate-binding protein 4 |
| UniProt Protein Name: | Guanylate-binding protein 4 |
| UniProt Synonym Protein Names: | GTP-binding protein 4; GBP-4; Guanine nucleotide-binding protein 4 |
| Protein Family: | Guanylate-binding protein |
| UniProt Gene Name: | GBP4 |
| UniProt Entry Name: | GBP4_HUMAN |