GAS8 Antibody (PACO19696)
- SKU:
- PACO19696
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GAS8 Antibody (PACO19696) |
| Antibody SKU: | PACO19696 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human GAS8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19696(GAS8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19696(GAS8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. |
| Synonyms: | growth arrest-specific 8 |
| UniProt Protein Function: | GAS8: Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility. Belongs to the GAS8 family.Protein type: CytoskeletalChromosomal Location of Human Ortholog: 16q24.3Cellular Component: Golgi apparatus; microtubuleMolecular Function: Rab GTPase bindingBiological Process: negative regulation of cell proliferation; sperm motility |
| UniProt Protein Details: | |
| NCBI Summary: | This gene includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer. The second intron contains an apparently intronless gene, C16orf3, that is transcribed in the opposite orientation. This gene is a putative tumor suppressor gene. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013] |
| UniProt Code: | O95995 |
| NCBI GenInfo Identifier: | 555290160 |
| NCBI Gene ID: | 2622 |
| NCBI Accession: | NP_001273134.1 |
| UniProt Secondary Accession: | O95995,Q2M234, B2RCT1, B7Z4U1, G3V1L5 |
| UniProt Related Accession: | O95995 |
| Molecular Weight: | 53,809 Da |
| NCBI Full Name: | growth arrest-specific protein 8 isoform b |
| NCBI Synonym Full Names: | growth arrest-specific 8 |
| NCBI Official Symbol: | GAS8 |
| NCBI Official Synonym Symbols: | GAS11 |
| NCBI Protein Information: | growth arrest-specific protein 8 |
| UniProt Protein Name: | Growth arrest-specific protein 8 |
| UniProt Synonym Protein Names: | Growth arrest-specific protein 11; GAS-11 |
| Protein Family: | Growth arrest-specific protein |
| UniProt Gene Name: | GAS8 |
| UniProt Entry Name: | GAS8_HUMAN |
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