GARS Monoclonal Antibody [PAT4E10AT] (CPAB0191)

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SKU:
CPAB0191
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT4E10AT
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:GARS Antibody
Product Sku:CPAB0191
Size:5μg
Host Species:Mouse
Immunogen:Anti-human GARS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GARS amino acids 43-289 purified from Ecoli.
Clone:PAT4E10AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:GARS antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:GARS is an (alpha)2 dimer which is a member of the class II family of tRNA synthetases. GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases which charge tRNAs with their cognate amino acids. GARS catalyzes the attachment of glycine to tRNA(Gly). In addition, GARS is able to produce diadenosine tetraphosphate (Ap4A), which is a universal pleiotropic signaling molecule required for cell regulation pathways, by direct condensation of two ATPs. GARS has been demonstrated to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Synonyms:Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS, GARS, CMT2D, DSMAV, HMN5, SMAD1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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