GALNT17 Antibody (PACO36746)
- SKU:
- PACO36746
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GALNT17 Antibody (PACO36746) |
| Antibody SKU: | PACO36746 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 17 protein (101-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO36746 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO36746 at dilution of 1:100. |
| Background: | May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. |
| Synonyms: | Polypeptide N-acetylgalactosaminyltransferase 17 (EC 2.4.1.41) (Polypeptide GalNAc transferase-like protein 3) (GalNAc-T-like protein 3) (pp-GaNTase-like protein 3) (Protein-UDP acetylgalactosaminyltransferase-like protein 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3) (Williams-Beuren syndrome chromosomal region 17 protein), GALNT17, WBSCR17 |
| UniProt Protein Function: | WBSCR17: May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. WBSCR17 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. |
| UniProt Protein Details: | Protein type:EC 2.4.1.41; Glycan Metabolism - O-glycan biosynthesis; Transferase; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q11.23 Cellular Component: Golgi membrane; integral to membrane Molecular Function:polypeptide N-acetylgalactosaminyltransferase activity; metal ion binding; carbohydrate binding Biological Process: protein amino acid glycosylation |
| NCBI Summary: | This gene encodes an N-acetylgalactosaminyltransferase. This gene is located centromeric to the common deleted region in Williams-Beuren syndrome (WBS), a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. This protein may play a role in membrane trafficking. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q6IS24 |
| NCBI GenInfo Identifier: | 51315852 |
| NCBI Gene ID: | 64409 |
| NCBI Accession: | Q6IS24.2 |
| UniProt Secondary Accession: | Q6IS24,Q8NFV9, Q9NTA8, |
| UniProt Related Accession: | Q6IS24 |
| Molecular Weight: | 598 |
| NCBI Full Name: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3 |
| NCBI Synonym Full Names: | Williams-Beuren syndrome chromosome region 17 |
| NCBI Official Symbol: | WBSCR17 |
| NCBI Official Synonym Symbols: | GALNT16; GALNT20; GALNTL3; GALNACT17; GalNAc-T5L |
| NCBI Protein Information: | putative polypeptide N-acetylgalactosaminyltransferase-like protein 3; galNAc-T-like protein 3; pp-GalNAc-transferase 20; pp-GaNTase-like protein 3; polypeptide GalNAc transferase 3; polypeptide GalNAc transferase-like protein 3; polypeptide N-acetylgalactosaminyltransferase-like 3; polypeptide N-acetylgalactosaminyltransferase WBSCR17; williams-Beuren syndrome chromosomal region 17 protein; protein-UDP acetylgalactosaminyltransferase-like protein 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16 |
| UniProt Protein Name: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3 |
| UniProt Synonym Protein Names: | Polypeptide GalNAc transferase-like protein 3; GalNAc-T-like protein 3; pp-GaNTase-like protein 3; Protein-UDP acetylgalactosaminyltransferase-like protein 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3; Williams-Beuren syndrome chromosomal region 17 protein |
| Protein Family: | Putative polypeptide N-acetylgalactosaminyltransferase-like protein |
| UniProt Gene Name: | WBSCR17 |
| UniProt Entry Name: | GLTL3_HUMAN |
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