GALNT14 Antibody (PACO38446)
- SKU:
- PACO38446
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | GALNT14 Antibody (PACO38446) |
| Antibody SKU: | PACO38446 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 14 protein (1-552AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: GALNT14 antibody at 2µg/ml. Lane 1: Rat gonad tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 65, 61, 62 kDa. Observed band size: 65 kDa. |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO38446 at dilution of 1:100. |
| Background: | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney. |
| Synonyms: | Polypeptide N-acetylgalactosaminyltransferase 14 (EC 2.4.1.41) (Polypeptide GalNAc transferase 14) (GalNAc-T14) (pp-GaNTase 14) (Protein-UDP acetylgalactosaminyltransferase 14) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14), GALNT14 |
| UniProt Protein Function: | GALNT14: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney. Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 2.4.1.41; Transferase; Glycan Metabolism - O-glycan biosynthesis; Membrane protein, integralChromosomal Location of Human Ortholog: 2p23.1Cellular Component: Golgi membraneMolecular Function: polypeptide N-acetylgalactosaminyltransferase activityBiological Process: O-glycan processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Alterations in this gene may play a role in cancer progression and response to chemotherapy. [provided by RefSeq, Jun 2016] |
| UniProt Code: | Q96FL9 |
| NCBI GenInfo Identifier: | 51316071 |
| NCBI Gene ID: | 79623 |
| NCBI Accession: | Q96FL9.1 |
| UniProt Secondary Accession: | Q96FL9,Q4ZG75, Q53SU1, Q53TJ0, Q8IVI4, Q9BRH1, Q9H827 Q9H9J8, B3KV89 |
| UniProt Related Accession: | Q96FL9 |
| Molecular Weight: | 61,588 Da |
| NCBI Full Name: | Polypeptide N-acetylgalactosaminyltransferase 14 |
| NCBI Synonym Full Names: | polypeptide N-acetylgalactosaminyltransferase 14 |
| NCBI Official Symbol: | GALNT14 |
| NCBI Official Synonym Symbols: | GALNT15; GalNac-T10; GalNac-T14 |
| NCBI Protein Information: | polypeptide N-acetylgalactosaminyltransferase 14 |
| UniProt Protein Name: | Polypeptide N-acetylgalactosaminyltransferase 14 |
| UniProt Synonym Protein Names: | Polypeptide GalNAc transferase 14; GalNAc-T14; pp-GaNTase 14; Protein-UDP acetylgalactosaminyltransferase 14; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 |
| Protein Family: | Polypeptide N-acetylgalactosaminyltransferase |
| UniProt Gene Name: | GALNT14 |
| UniProt Entry Name: | GLT14_HUMAN |
| Antibodies |
| GALNT14 Antibody (PACO09402) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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