Growth Factors & Cytokines Recombinant Proteins
Galectin-3 Recombinant Protein (RPES4754)
- SKU:
- RPES4754
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Growth Factors & Cytokines
Description
Galectin-3 Recombinant Protein
Leukotriene A-4 hydrolase; also known as LTA-4 hydrolase; Leukotriene A (4) hydrolase; LTA4H and LTA4; is cytoplasm protein which belongs to the peptidase M1 family. The epoxide of leukotriene A4 is hydrolyzed to form leukotriene B4 by LTA4H. This enzyme also has some peptidase activity. Leukotrienes (LTs) are a group of structurally related lipid mediators that play a role in the development and perpetuation of inflammatory and allergic reactions. Arachidonic acid is converted into the unstable intermediate epoxide LTA4; which may be conjugated with glutathione to form spasmogenic LTC4; or hydrolyzed into proinflammatory lipid mediator LTB4 in a reaction controlled by Leukotriene A4 hydrolase (LTA4H). LTB4 is a neutrophil chemoattractant (classic attractant) and induces adherence and aggregation of leukocytes to vascular endothelium, as well as immune responses. LTA4H also has an ion-dependent arginyl aminopeptidase activity that is highly efficient and specific, in addition to its epoxide hydrolase activity. LTA4H is regarded as a therapeutic target for inflammation. Galectin-3 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Galectin-3 Recombinant Protein (RPES4754) |
| Product Code: | RPES4754 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Galectin-3, Gal-3, 35 kDa Lectin, Carbohydrate-Binding Protein 35, CBP35, Galactose-Specific Lectin 3, Galactoside-Binding Protein, GALBP, IgE-Binding Protein, L-31, Laminin-Binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2, P35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2 |
| Accession: | P17931 |
| Sequence: | Met 1-Ile 250 |
| Fusion tag: | |
| Activity: | Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 3-15 µg/ml. |
| Endotoxin: | <5 EU per 1 mg of the protein as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human Galectin3 (P17931) (Met 1-Ile 250) was expressed and purified. |
| Purity: | > 97 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.1 kDa |
| AP Mol Mass: | 30 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Human Galectin-3/LGALS3 Recombinant Protein (RPES4635)
Developmental Biology Recombinant Proteins
Mouse Galectin/LGALS1 Recombinant Protein (RPES3784)
Cell Death Recombinant Proteins
Rat Galectin/LGALS1 Recombinant Protein (RPES5240)
Cell Death Recombinant Proteins