Galectin 3/LGALS3 Monoclonal Antibody (CAB22768)

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SKU:
CAB22768
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF
Applications:
IP

Description

Product Name:Galectin 3/LGALS3 Monoclonal Antibody
Product Code:CAB22768
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunofluorescence, Immunoprecipitation
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC58277
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IF/ICC, IP, ELISA
Key Applications:Western blotting, Immunofluorescence, Immunoprecipitation
Recommended Dilution:WB 1:2000-1:10000, IF/ICC 1:100-1:500, IP 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:HeLa, Rat spleen, NIH/3T3, C2C12
Cellular Location:Cytoplasm, Nucleus, Secreted
Customer Validation:WB(Rattus norvegicus)

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 human Galectin 3/LGALS3 (NP_002297.2).
Sequence:MADNF SLHDA LSGSG NPNPQ GWPGA WGNQP AGAGG YPGAS YPGAY PGQAP PGAYP GQAPP GAYPG APGAY PGAPA PGVYP GPPSG PGAYP SSGQP SATGA YPATG PYGAP AGPLI VPYNL PLPGG VVPRM LITIL GTVKP NANRI ALDFQ RGNDV AFHFN PRFNE NNRRV IVCNT KLDNN WGREE RQSVF PFESG KPFKI QVLVE PDHFK VAVND AHLLQ YNHRV KKLNE ISKLG ISGDI DLTSA SYTMI
Synonyms:L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2
Calculated MW:26kDa
Observed MW:28kDa
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system_update_altDatasheetHuman Galectin-3/LGALS3 Recombinant Protein Galectin-3(LGALS3) is also known as Galactose-specific lectin 3; Mac-2 antigen; Carbohydrate-binding protein 35; Laminin-bind