gag-pol Antibody (PACO33588)
- SKU:
- PACO33588
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | gag-pol Antibody (PACO33588) |
| Antibody SKU: | PACO33588 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human immunodeficiency virus type 1 group M subtype B |
| Immunogen: | Recombinant Human immunodeficiency virus type 1 group M subtype B Gag-Pol polyprotein protein (1-440AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)], gag-pol |
| UniProt Protein Function: | Gag-Pol polyprotein: Mediates, with Gag polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. At low concentration, the polyprotein would promote translation, whereas at high concentration, the polyprotein would encapsidate genomic RNA and then shutt off translation.Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus (). Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P04585 |
| NCBI GenInfo Identifier: | 28872819 |
| NCBI Gene ID: | 155348 |
| NCBI Accession: | NP_057849.4 |
| UniProt Secondary Accession: | P04585,O09777, Q9WJC5 |
| UniProt Related Accession: | P04585 |
| Molecular Weight: | 24kDa (mature); 55kDa; 41kDa (precursors) |
| NCBI Full Name: | Gag-Pol |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | gag-pol |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | Gag-Pol; Gag-Pol polyprotein; Gag-Pol Transframe peptide; aspartic peptidase; p66 subunit; integrase; reverse transcriptase p51 subunit |
| UniProt Protein Name: | Gag-Pol polyprotein |
| UniProt Synonym Protein Names: | Pr160Gag-PolCleaved into the following 11 chains:Matrix protein p17; MA; Capsid protein p24; CA; Spacer peptide p2; Nucleocapsid protein p7; NC; Transframe peptide; TF; p6-pol; p6*; Protease (EC:3.4.23.16)Alternative name(s):PR; Retropepsin |
| Protein Family: | |
| UniProt Gene Name: | P04585. |
| UniProt Entry Name: | POL_HV1H2 |
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