gag Antibody (PACO34646)
- SKU:
- PACO34646
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | gag Antibody (PACO34646) |
| Antibody SKU: | PACO34646 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Moloney murine leukemia virus |
| Immunogen: | Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release. |
| Synonyms: | Gag polyprotein (Pr65gag) (Core polyprotein) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10-Gag (NC-gag)], gag |
| UniProt Protein Function: | Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P03332 |
| NCBI GenInfo Identifier: | 9626959 |
| NCBI Gene ID: | 1491870 |
| NCBI Accession: | NP_057934.1 |
| UniProt Secondary Accession: | P03332,Q9WJP4 |
| UniProt Related Accession: | P03332 |
| Molecular Weight: | 57.6 kDa |
| NCBI Full Name: | Pr65 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | gag |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | Pr65; p15 MA; pp12; p30 CA; p10 NC |
| UniProt Protein Name: | Gag polyprotein |
| UniProt Synonym Protein Names: | Core polyprotein |
| Protein Family: | Gag polyprotein |
| UniProt Gene Name: | gag |
| UniProt Entry Name: | GAG_MLVMS |
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