Description
Antibody Name: | gag Antibody (PACO33552) |
Antibody SKU: | PACO33552 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human immunodeficiency virus type 1 group M subtype B |
Immunogen: | Recombinant Human immunodeficiency virus type 1 group M subtype B Gag polyprotein protein (2-132AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).1 Publication Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus (By similarity). Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA (By similarity). |
Synonyms: | Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Spacer peptide 2 (SP2) (p1); p6-gag], gag |
UniProt Protein Function: | Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P04591 |
NCBI GenInfo Identifier: | 9629360 |
NCBI Gene ID: | 155030 |
NCBI Accession: | NP_057850.1 |
UniProt Secondary Accession: | P04591 |
UniProt Related Accession: | P04591,Q77YG1 |
Molecular Weight: | 162,042 Da |
NCBI Full Name: | Pr55(Gag) |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | gag |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | Pr55(Gag); matrix; capsid; nucleocapsid; p2; p6; p1 |
UniProt Protein Name: | Gag polyprotein |
UniProt Synonym Protein Names: | p1 |
Protein Family: | Proteinase |
UniProt Gene Name: | gag |
UniProt Entry Name: | GAG_HV1H2 |