Description
| Antibody Name: | gag Antibody (PACO33552) |
| Antibody SKU: | PACO33552 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human immunodeficiency virus type 1 group M subtype B |
| Immunogen: | Recombinant Human immunodeficiency virus type 1 group M subtype B Gag polyprotein protein (2-132AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).1 Publication Matrix protein p17: Targets the polyprotein to the plasma membrane via a multipartite membrane-binding signal, that includes its myristoylated N-terminus (By similarity). Matrix protein is part of the pre-integration complex. Implicated in the release from host cell mediated by Vpu. Binds to RNA (By similarity). |
| Synonyms: | Gag polyprotein (Pr55Gag) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Spacer peptide 2 (SP2) (p1); p6-gag], gag |
| UniProt Protein Function: | Gag polyprotein: Mediates, with Gag-Pol polyrotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P04591 |
| NCBI GenInfo Identifier: | 9629360 |
| NCBI Gene ID: | 155030 |
| NCBI Accession: | NP_057850.1 |
| UniProt Secondary Accession: | P04591 |
| UniProt Related Accession: | P04591,Q77YG1 |
| Molecular Weight: | 162,042 Da |
| NCBI Full Name: | Pr55(Gag) |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | gag |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | Pr55(Gag); matrix; capsid; nucleocapsid; p2; p6; p1 |
| UniProt Protein Name: | Gag polyprotein |
| UniProt Synonym Protein Names: | p1 |
| Protein Family: | Proteinase |
| UniProt Gene Name: | gag |
| UniProt Entry Name: | GAG_HV1H2 |