gadA Antibody (PACO33992)
- SKU:
- PACO33992
- Product Type:
- Antibody
- Reactivity:
- Bacteria - Escherichia coli
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | gadA Antibody (PACO33992) |
| Antibody SKU: | PACO33992 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Escherichia coli |
| Immunogen: | Recombinant Escherichia coli Glutamate decarboxylase α protein (1-466AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acid, c conditions. The ability to survive transit through the acid, c conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria. |
| Synonyms: | Glutamate decarboxylase α (GAD-alpha) (EC 4.1.1.15), gadA, gadS |
| UniProt Protein Function: | Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria. |
| UniProt Protein Details: | |
| NCBI Summary: | RpoS regulon. [More information is available at EcoGene: EG50009]. GadA, a glutamate decarboxylase enzyme, is part of the glutamate-dependent acid resistance system 2 (AR2) which confers resistance to extreme acid conditions. [More information is available at EcoCyc: EG50009]. |
| UniProt Code: | P69908 |
| NCBI GenInfo Identifier: | 16131389 |
| NCBI Gene ID: | 948027 |
| NCBI Accession: | NP_417974.1 |
| UniProt Secondary Accession: | P69908,P80063, Q2M7H9 |
| UniProt Related Accession: | P69908 |
| Molecular Weight: | 52,685 Da |
| NCBI Full Name: | glutamate decarboxylase A, PLP-dependent |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | gadA |
| NCBI Official Synonym Symbols: | ECK3502; gadS; JW3485 |
| NCBI Protein Information: | glutamate decarboxylase A, PLP-dependent |
| UniProt Protein Name: | Glutamate decarboxylase alpha |
| UniProt Synonym Protein Names: | |
| Protein Family: | Glutamate decarboxylase |
| UniProt Gene Name: | gadA |
| UniProt Entry Name: | DCEA_ECOLI |
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