G Antibody (PACO34998)
- SKU:
- PACO34998
- Product Type:
- Antibody
- Reactivity:
- Virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | G Antibody (PACO34998) |
| Antibody SKU: | PACO34998 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rabies virus |
| Immunogen: | Recombinant Rabies virus Glycoprotein protein (20-459AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acid, c pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. |
| Synonyms: | Glycoprotein, G |
| UniProt Protein Function: | Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A3RM22 |
| NCBI GenInfo Identifier: | 158513484 |
| NCBI Gene ID: | |
| NCBI Accession: | A3RM22.1 |
| UniProt Secondary Accession: | A3RM22,Q58FH1 |
| UniProt Related Accession: | A3RM22 |
| Molecular Weight: | 51.4 kDa |
| NCBI Full Name: | Glycoprotein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Glycoprotein |
| UniProt Synonym Protein Names: | |
| Protein Family: | Glycoprotein |
| UniProt Gene Name: | G |
| UniProt Entry Name: | GLYCO_RABVI |
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