Antibody Name:	G Antibody (PACO34962)
Antibody SKU:	PACO34962
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Human respiRatory syncytial virus A
Immunogen:	Recombinant Human respiratory syncytial virus A Major surface glycoprotein G protein (67-298AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:

Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcγ receptors.

Synonyms:

Major surface glycoprotein G (Attachment glycoprotein G) (Membrane-bound glycoprotein) (mG), G

UniProt Protein Function:	Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities.
UniProt Protein Details:
NCBI Summary:
UniProt Code:	P03423
NCBI GenInfo Identifier:	138294
NCBI Gene ID:
NCBI Accession:	P03423.1
UniProt Secondary Accession:	P03423,Q77YB0
UniProt Related Accession:	P03423
Molecular Weight:	29.3 kDa
NCBI Full Name:	Major surface glycoprotein G
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:	Major surface glycoprotein G
UniProt Synonym Protein Names:	Attachment glycoprotein G; Membrane-bound glycoprotein; mG
Protein Family:
UniProt Gene Name:	G
UniProt Entry Name:	GLYC_HRSVA