Description
| Antibody Name: | FYTTD1 Antibody (PACO39042) |
| Antibody SKU: | PACO39042 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human UAP56-interacting factor protein (1-318AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: FYTTD1 antibody at 4µg/ml. Lane 1: A375 whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36, 34, 29, 15 kDa. Observed band size: 36 kDa. |
| Background: | Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. |
| Synonyms: | UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3), FYTTD1, UIF |
| UniProt Protein Function: | FYTTD1: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. Belongs to the UIF family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q29Cellular Component: nuclear speck; nucleoplasmMolecular Function: mRNA binding; protein bindingBiological Process: mRNA export from nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96QD9 |
| NCBI GenInfo Identifier: | 284018159 |
| NCBI Gene ID: | 84248 |
| NCBI Accession: | Q96QD9.3 |
| UniProt Secondary Accession: | Q96QD9,Q96SL9, A8MY74, B2RCB2, B7Z3R4, B7Z7V1, B7Z8I0 B7ZAJ3, C9J7P6, C9JNG6 |
| UniProt Related Accession: | Q96QD9 |
| Molecular Weight: | 14,524 Da |
| NCBI Full Name: | UAP56-interacting factor |
| NCBI Synonym Full Names: | forty-two-three domain containing 1 |
| NCBI Official Symbol: | FYTTD1 |
| NCBI Official Synonym Symbols: | UIF |
| NCBI Protein Information: | UAP56-interacting factor |
| UniProt Protein Name: | UAP56-interacting factor |
| UniProt Synonym Protein Names: | Forty-two-three domain-containing protein 1; Protein 40-2-3 |
| Protein Family: | UAP56-interacting factor |
| UniProt Gene Name: | FYTTD1 |
| UniProt Entry Name: | UIF_HUMAN |
