Description
Antibody Name: | FYTTD1 Antibody (PACO39042) |
Antibody SKU: | PACO39042 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human UAP56-interacting factor protein (1-318AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: FYTTD1 antibody at 4µg/ml. Lane 1: A375 whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 36, 34, 29, 15 kDa. Observed band size: 36 kDa. |
Background: | Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. |
Synonyms: | UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3), FYTTD1, UIF |
UniProt Protein Function: | FYTTD1: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. Belongs to the UIF family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3q29Cellular Component: nuclear speck; nucleoplasmMolecular Function: mRNA binding; protein bindingBiological Process: mRNA export from nucleus |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96QD9 |
NCBI GenInfo Identifier: | 284018159 |
NCBI Gene ID: | 84248 |
NCBI Accession: | Q96QD9.3 |
UniProt Secondary Accession: | Q96QD9,Q96SL9, A8MY74, B2RCB2, B7Z3R4, B7Z7V1, B7Z8I0 B7ZAJ3, C9J7P6, C9JNG6 |
UniProt Related Accession: | Q96QD9 |
Molecular Weight: | 14,524 Da |
NCBI Full Name: | UAP56-interacting factor |
NCBI Synonym Full Names: | forty-two-three domain containing 1 |
NCBI Official Symbol: | FYTTD1 |
NCBI Official Synonym Symbols: | UIF |
NCBI Protein Information: | UAP56-interacting factor |
UniProt Protein Name: | UAP56-interacting factor |
UniProt Synonym Protein Names: | Forty-two-three domain-containing protein 1; Protein 40-2-3 |
Protein Family: | UAP56-interacting factor |
UniProt Gene Name: | FYTTD1 |
UniProt Entry Name: | UIF_HUMAN |