FXYD4 Antibody (PACO09370)
- SKU:
- PACO09370
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FXYD4 Antibody (PACO09370) |
| Antibody SKU: | PACO09370 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human FXYD4 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FXYD domain containing ion transport regulator 4;FXYD4;CHIF ; |
| UniProt Protein Function: | FXYD4: a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, May 2010]Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 10q11.21Cellular Component: integral to membrane; plasma membraneMolecular Function: potassium channel activity; ATPase bindingBiological Process: transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, May 2010] |
| UniProt Code: | P59646 |
| NCBI GenInfo Identifier: | 114152806 |
| NCBI Gene ID: | 53828 |
| NCBI Accession: | P59646.2 |
| UniProt Secondary Accession: | P59646,Q6UWZ1, Q7Z4M5 |
| UniProt Related Accession: | P59646 |
| Molecular Weight: | |
| NCBI Full Name: | FXYD domain-containing ion transport regulator 4 |
| NCBI Synonym Full Names: | FXYD domain containing ion transport regulator 4 |
| NCBI Official Symbol: | FXYD4 |
| NCBI Official Synonym Symbols: | CHIF |
| NCBI Protein Information: | FXYD domain-containing ion transport regulator 4; channel-inducing factor |
| UniProt Protein Name: | FXYD domain-containing ion transport regulator 4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | FXYD domain-containing ion transport regulator |
| UniProt Gene Name: | FXYD4 |
| UniProt Entry Name: | FXYD4_HUMAN |
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