FXN / Frataxin Polyclonal Antibody
- SKU:
- CAB21423
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | FXN / Frataxin Polyclonal Antibody |
| Product Code: | CAB21423 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Mitochondrion |
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2). |
| Sequence: | LRTDI DATCT PRRAS SNQRG LNQIW NVKKQ SVYLM NLRKS GTLGH PGSLD ETTYE RLAEE TLDSL AEFFE DLADK PYTFE DYDVS FGSGV LTVKL GGDLG TYVIN KQTPN KQIWL SSPSS GPKRY DWTGK NWVYS HDGVS LHELL AAELT KALKT KLDLS SLAYS GKDA |
| Synonyms: | FA, X25, CyaY, FARR, FRDA |
| Calculated MW: | 23kDa |
| Observed MW: | Refer to figures |
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