FUS Polyclonal Antibody
- SKU:
- CAB21830
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IP
Description
| Product Name: | FUS Polyclonal Antibody |
| Product Code: | CAB21830 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Nucleus |
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1). |
| Sequence: | TIESV ADYFK QIGII KTNKK TGQPM INLYT DRETG KLKGE ATVSF DDPPS AKAAI DWFDG KEFSG NPIKV SFATR RADFN RGGGN GRGGR GRGGP MGRGG YGGGG SGGGG RGGFP SGGGG GGGQQ RAGDW KCPNP TCENM NFSWR NECNQ CKAPK PDGPG GGPGG SHMGG NYGDD RRGGR GGYDR GGYRG RGGDR GGFRG GRGGG DRGGF GPGKM DSRGE HRQDR RERPY |
| Synonyms: | TLS, ALS6, ETM4, FUS1, POMP75, altFUS, HNRNPP2 |
| Calculated MW: | 53kDa |
| Observed MW: | Refer to figures |
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