FRMD7 Antibody (PACO60136)
- SKU:
- PACO60136
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FRMD7 Antibody (PACO60136) |
| Antibody SKU: | PACO60136 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human FERM domain-containing protein 7 protein (464-617AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: U87 whole cell lysate. All lanes: FRMD7 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 82, 80 kDa. Observed band size: 82 kDa. |
 | IHC image of PACO60136 diluted at 1:400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO60136 diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability. |
| Synonyms: | FERM domain-containing protein 7, FRMD7 |
| UniProt Protein Function: | FRMD7: Plays a role in neurite development. May play a specific role in the control of eye movement and gaze stability. Defects in FRMD7 are the cause of nystagmus congenital X- linked type 1 (NYS1). NYS1 is a condition defined as conjugated, spontaneous and involuntary ocular oscillations that appear at birth or during the first three months of life. Other associated features may include mildly decreased visual acuity, strabismus, astigmatism, and occasionally head nodding. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: Xq26.2Cellular Component: cell soma; extracellular space; growth cone; neuron projectionDisease: Nystagmus 1, Congenital, X-linked |
| UniProt Protein Details: | |
| NCBI Summary: | Mutations in this gene are associated with X-linked congenital nystagmus. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q6ZUT3 |
| NCBI GenInfo Identifier: | 74749680 |
| NCBI Gene ID: | 90167 |
| NCBI Accession: | Q6ZUT3.1 |
| UniProt Secondary Accession: | Q6ZUT3,Q5JX99, C0LLJ3 |
| UniProt Related Accession: | Q6ZUT3 |
| Molecular Weight: | 79,793 Da |
| NCBI Full Name: | FERM domain-containing protein 7 |
| NCBI Synonym Full Names: | FERM domain containing 7 |
| NCBI Official Symbol: | FRMD7 |
| NCBI Official Synonym Symbols: | NYS; NYS1; XIPAN |
| NCBI Protein Information: | FERM domain-containing protein 7 |
| UniProt Protein Name: | FERM domain-containing protein 7 |
| UniProt Synonym Protein Names: | |
| Protein Family: | FERM domain-containing protein |
| UniProt Gene Name: | FRMD7 |
| UniProt Entry Name: | FRMD7_HUMAN |
Related Products
Human TP53 antibody(p53 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
OSTN Antibody
Overview Product Name:OSTN AntibodyProduct Code:PACO64881Size:50µLTarget Names:OSTNSpecies Reactivity:HumanHost
CYP2A13 Antibody
Overview Product Name:CYP2A13 AntibodyProduct Code:PACO64657Size:50µLTarget Names:CYP2A13Species Reactivity:Human, Mouse
OR13C8 Antibody
Overview Product Name:OR13C8 AntibodyProduct Code:PACO64869Size:50µLTarget Names:OR13C8Species Reactivity:HumanH
TTC14 Antibody
Overview Product Name:TTC14 AntibodyProduct Code:PACO64997Size:50µLTarget Names:TTC14Species Reactivity:HumanHos