FRMD5 Antibody (PACO46726)
- SKU:
- PACO46726
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FRMD5 Antibody (PACO46726) |
| Antibody SKU: | PACO46726 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human FERM domain-containing protein 5 protein (295-504AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: FRMD5 antibody at 16 µg/ml. Lane 1: Mouse kidney tissue. Lane 2: Mouse heart tissue. Lane 3: Mouse skeletal muscle tissue. Lane 4: Mouse lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 66, 64 kDa. Observed band size: 65 kDa.. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO46726 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human glioma using PACO46726 at dilution of 1:100. |
| Synonyms: | FERM domain-containing protein 5, FRMD5 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q7Z6J6 |
| NCBI GenInfo Identifier: | 34190399 |
| NCBI Gene ID: | 26269 |
| NCBI Accession: | BC014679 |
| UniProt Secondary Accession: | Q7Z6J6,Q6UWN4, Q8IWE1, Q9NRP5, Q9UKC4, B2RB40, D3DP41 G5E9Z0 |
| UniProt Related Accession: | Q7Z6J6,Q9NRD0 |
| Molecular Weight: | 32,426 Da |
| NCBI Full Name: | Homo sapiens F-box protein 8, mRNA |
| NCBI Synonym Full Names: | F-box protein 8 |
| NCBI Official Symbol: | FBXO8 |
| NCBI Official Synonym Symbols: | FBS; DC10; FBX8 |
| NCBI Protein Information: | F-box only protein 8 |
| UniProt Protein Name: | FERM domain-containing protein 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | FRMD5 |
| UniProt Entry Name: | FRMD5_HUMAN |
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