Description
system_update_alt Datasheet
Product Name: | Frataxin Antibody |
Product Sku: | CPAB0664 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human Frataxin mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Frataxin protein 42-21 amino acids purified from Ecoli. |
Clone: | PAT10E11AT. |
Reactivity: | Other bodies |
Applications: | ELISA, Flow Cytometry |
Purification Method: | Frataxin antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | Frataxin is a mitochondrial iron binding protein that is part of the FRATAXIN family. Frataxin functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Frataxin plays a role in iron homeostasis. Frataxin is an anti-apoptotic protein which prevents mitochondrial damage and reactive oxygen species (ROS) production. |
Synonyms: | FXN, Friedreich ataxia protein, Frataxin mitochondrial, FRDA, X25, FA, CyaY, FARR, MGC57199, Frataxin. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |