FPR3 Antibody (PACO53018)
- SKU:
- PACO53018
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FPR3 Antibody (PACO53018) |
| Antibody SKU: | PACO53018 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human N-formyl peptide receptor 3 protein (307-353AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO53018 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO53018 at dilution of 1:100 and Cy3-congugated Goat Anti-Rabbit IgG. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO53018 at dilution of 1:100. |
| Background: | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Synonyms: | N-formyl peptide receptor 3 (FMLP-related receptor II) (FMLP-R-II) (Formyl peptide receptor-like 2), FPR3, FPRH1 FPRL2 |
| UniProt Protein Function: | FPR3: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19q13.3-q13.4Cellular Component: plasma membraneBiological Process: cell motility; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P25089 |
| NCBI GenInfo Identifier: | 38258904 |
| NCBI Gene ID: | 2359 |
| NCBI Accession: | P25089.2 |
| UniProt Secondary Accession: | P25089 |
| UniProt Related Accession: | P25089 |
| Molecular Weight: | 39,965 Da |
| NCBI Full Name: | N-formyl peptide receptor 3 |
| NCBI Synonym Full Names: | formyl peptide receptor 3 |
| NCBI Official Symbol: | FPR3 |
| NCBI Official Synonym Symbols: | FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; FMLP-R-II; FML2_HUMAN |
| NCBI Protein Information: | N-formyl peptide receptor 3 |
| UniProt Protein Name: | N-formyl peptide receptor 3 |
| UniProt Synonym Protein Names: | FMLP-related receptor II; FMLP-R-II; Formyl peptide receptor-like 2 |
| Protein Family: | FK506-binding protein |
| UniProt Gene Name: | FPR3 |
| UniProt Entry Name: | FPR3_HUMAN |
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