FOXRED2 Antibody (PACO52534)
- SKU:
- PACO52534
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | FOXRED2 Antibody (PACO52534) |
| Antibody SKU: | PACO52534 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human FAD-dependent oxidoreductase domain-containing protein 2 protein (501-684AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO52534 at dilution of 1:100. |
| Background: | Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. |
| Synonyms: | FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation), FOXRED2, ERFAD |
| UniProt Protein Function: | FOXRED2: Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Belongs to the FOXRED2 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 22q12.3Cellular Component: endoplasmic reticulum lumenMolecular Function: protein binding; FAD binding; oxidoreductase activity; glycoprotein bindingBiological Process: ER-associated protein catabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IWF2 |
| NCBI GenInfo Identifier: | 156139139 |
| NCBI Gene ID: | 80020 |
| NCBI Accession: | NP_079231.4 |
| UniProt Secondary Accession: | Q8IWF2,Q8N378, Q96BD1, Q9H5L5, Q9H6M8, B2RDI4 |
| UniProt Related Accession: | Q8IWF2 |
| Molecular Weight: | 41,157 Da |
| NCBI Full Name: | FAD-dependent oxidoreductase domain-containing protein 2 |
| NCBI Synonym Full Names: | FAD-dependent oxidoreductase domain containing 2 |
| NCBI Official Symbol: | FOXRED2 |
| NCBI Official Synonym Symbols: | ERFAD |
| NCBI Protein Information: | FAD-dependent oxidoreductase domain-containing protein 2; endoplasmic reticulum flavoprotein associated with degradation |
| UniProt Protein Name: | FAD-dependent oxidoreductase domain-containing protein 2 |
| UniProt Synonym Protein Names: | Endoplasmic reticulum flavoprotein associated with degradation |
| Protein Family: | FAD-dependent oxidoreductase domain-containing protein |
| UniProt Gene Name: | FOXRED2 |
| UniProt Entry Name: | FXRD2_HUMAN |
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