Description
| Antibody Name: | FOXN4 Antibody |
| Antibody SKU: | PACO02453 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human FoxN4. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FOXN4; Forkhead box protein N4 |
| UniProt Protein Function: | FOXN4: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell development/differentiation; DNA-binding; Transcription factorChromosomal Location of Human Ortholog: 12q24.11Cellular Component: nucleusMolecular Function: chromatin binding; transcription factor activityBiological Process: heart looping; positive regulation of transcription, DNA-dependent; regulation of heart contraction; regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96NZ1 |
| NCBI GenInfo Identifier: | 71153520 |
| NCBI Gene ID: | 121643 |
| NCBI Accession: | Q96NZ1.2 |
| UniProt Secondary Accession: | Q96NZ1,Q6ZMR4, Q96NZ0 |
| UniProt Related Accession: | Q96NZ1 |
| Molecular Weight: | 36,025 Da |
| NCBI Full Name: | Forkhead box protein N4 |
| NCBI Synonym Full Names: | forkhead box N4 |
| NCBI Official Symbol: | FOXN4 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | forkhead box protein N4 |
| UniProt Protein Name: | Forkhead box protein N4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Forkhead box protein |
| UniProt Gene Name: | FOXN4 |
| UniProt Entry Name: | FOXN4_HUMAN |